| Engine | Years Active |
| Abbott-Detroit | 1910-11 |
| Acme | 1909 |
| Adams | 1914 |
| Adams | 1947 |
Alco  |
1909-11, 14-15 |
|
Alfa Romeo |
1936-41, 46-53, 56, 89-91 |
| Allen-Kingston | 1909-10 |
| Alta | 1962 |
| Ambler | 1929, 36-38 |
| AMC | 1952, 72, 76-79 |
|
American |
1909-10 |
| Amplex | 1910-11 |
| Anzani | 1926 |
|
Apperson |
1909-11, 13-16 |
| Argyle | 1926 |
| Aston Martin | 1963 |
| Atlas | 1909 |
| Auburn | 1909 |
|
Auto Union |
1937 |
| Autocar | 1909 |
|
Ballot |
1919-22 |
| Barnes | 1983 |
| Bender | 1918 |
| Bentley | 1922 |
|
Benz |
1909-15 |
| Black Crow | 1910 |
| Boeing | 1962 |
| Brett | 1921 |
| Brisko | 1936-41, 46, 49 |
| Brown | 1915, 19 |
| Bugatti | 1914-15, 23, 26-28, 32, 34, 36, 47 |
|
Buick |
1909-16, 30-39, 49, 52-54, 62-64, 68-70, 84-96 |
|
Cadillac |
1909, 13, 50, 52-54, 60, 62-68 |
| Carew | 1936 |
| Carter | 1914 |
| Case | 1911-13, 15 |
| Chadwick | 1909, 14 |
| Chalmers | 1914-16 |
|
Chalmers-Detroit |
1909 |
|
Chevrolet |
1914-15, 30, 47-53, 55, 61-77, 79-94, 2002-05, 12-25 |
| Christie | 1905 |
| Chrysler | 1928-33, 49, 52-54, 57-58, 60-61, 63, 67 |
| Cino | 1910-13, 15-17 |
| Clemons | 1928, 31-34, 38, 46-48 |
| Climax | 1961, 63 |
|
Colburn |
1909 |
| Colby | 1911 |
|
Cole |
1910-12 |
| Columbia | 1909-10, 13 |
| Comet | 1909, 18 |
| Continental | 1912 |
| Cooper | 1931-35, 37 |
| Corbin | 1909-11 |
| Cornelian | 1914-15 |
|
Cosworth |
1969, 75-93, 2007-08 |
| Cragar | 1935-38, 46, 49, 51 |
| Crawford | 1917 |
| Crower | 1977-78 |
| Cummins | 1931, 34, 50, 52 |
| Curtis | 1915-16 |
| Curtis | 1931 |
| Cutting | 1910-12 |
| De Dietrich | 1905 |
|
Decauville |
1905 |
|
Delage |
1914-23, 29 |
| DeSoto | 1933-34, 52, 58 |
|
DGS |
1975-81 |
|
D. O. Fronty
|
1946 |
| Dodge | 1916, 33, 36, 55, 65, 73 |
| Donovan | 1980-82 |
| Dorris | 1909 |
| Dreyer | 1946-48 |
|
Duesenberg |
1912-38, 47-48 |
| duPont | 1930 |
| Duray | 1931-32, 38-41, 46-51 |
| Durocar | 1909, 11 |
| Edwards | 1915 |
| Elmore | 1909, 15 |
| Emden | 1915 |
| EMF | 1910-12 |
| ERA | 1936, 47 |
| Excelsior | 1914 |
| Fageol | 1948-49 |
|
Falcar |
1909-12, 15 |
| Ferrari | 1952, 54, 56-58 |
|
Fiat |
1905, 09-15, 17, 22, 24-25 |
| Firestone-Columbus | 1910-12 |
| Flanders | 1911-12 |
|
Ford |
1909, 11-13, 15-16, 19, 22-23, 25, 31-37, 46-48, 50-55, 58, 62-73, 92-2006 |
|
Foyt |
1972-79 |
| Franklin | 1909 |
|
Frontenac |
1916-25, 27-29, 31 |
| Fronty-Ford | 1922, 24-27, 29-33 |
| GE | 1968 |
| G. J. G. | 1912 |
| GMC | 1952-54, 56, 63-66, 68 |
| Graham | 1932-35 |
| Great Western | 1910, 14 |
| Green | 1925, 27-29 |
| Greenfield | 1994-95 |
| Gregoire | 1920 |
|
Gurney-Weslake Ford
|
1967-70 |
| Gyrotary | 1918 |
|
HAL |
1946-49, 56 |
| Haynes | 1909, 16, 18 |
| Henderson | 1915 |
| Hercules | 1915-16 |
| Herreshoff | 1912 |
| Hispano-Suiza | 1913 |
| Hisso | 1932 |
|
Honda |
1986, 94-2025 |
| Hoskin | 1919 |
| Houpt-Rockwell | 1910 |
|
Hudson |
1913-14, 16-20, 31-36, 52-53, 56 |
| Hupmobile | 1914, 32 |
|
Ilmor |
1994 |
| Interstate | 1911, 13 |
| Isotta | 1909, 13-15 |
| Italia | 1914 |
|
Jackson |
1909-11 |
| Jaguar | 1955, 57-58 |
|
Judd |
1987-92 |
| K & M | 1926-27 |
| Kaiser | 1952 |
| Keeton | 1913 |
| Kinnear | 1913 |
| Kissel | 1909-10, 16 |
| Klinekar | 1912 |
| Knight | 1912 |
| Knight | 1913 |
| Knox | 1909-12 |
| Lagonda | 1946 |
| Lancia | 1910 |
|
Lencki |
1933-35, 39-41, 46-49, 63 |
| Lexington | 1909-12 |
| Liberty | 1918 |
|
Lincoln |
1933, 53-55, 62-64, 66-70 |
| Locomobile | 1909, 11, 13, 20, 26-27 |
| Lotus | 2012 |
|
Lozier |
1909-15 |
| Lycoming | 1930-33, 35 |
| Macomber | 1913 |
| Marion | 1909-10, 13 |
|
Marmon |
1909-11, 13-16, 37 |
| Marquette | 1916 |
|
Maserati |
1930, 36-41, 46-51, 53, 57-59, 64-65 |
|
Mason |
1912 |
| Matheson | 1910 |
|
Maxwell |
1905, 09, 11-12, 14-16 |
| McDowell | 1937-40, 46-56 |
| McFarlan | 1910-12 |
| Menard | 1993, 95-96 |
|
Mercedes |
1909-17, 19-20, 23-25, 27, 30-31, 36-37, 46-48, 94-2000 |
|
Mercer |
1910-19, 31 |
|
Mercury |
1941, 47-53 |
| Meyer & Drake | 1949 |
| Midland | 1910-12 |
|
Miller |
1917-41, 46-51 |
| Milodon | 1982 |
| Mitchell | 1909, 15 |
| Moon | 1909, 14-15 |
| Morton & Brett | 1930-33, 35, 37-38 |
| Moser-Chevy | 1975 |
| Napier | 1905, 15 |
| Nash | 1952 |
| Nash-Healey | 1951, 54-55 |
|
National |
1909-17 |
|
Nissan |
1997-2002 |
| Novi | 1941, 46-66 |
| Nyberg | 1913 |
| Oakland | 1930, 32, 34 |
|
Offenhauser |
1935-41, 46-83 |
| Ogren | 1918 |
| Ohio | 1911-13 |
|
Oldsmobile |
1909-10, 51-52, 55-56, 62-68, 97-2001 |
| Ono | 1914-16 |
| Opel | 1912 |
| Ostewig | 1918 |
| Overland | 1909-10, 15 |
|
Packard |
1917-19, 23, 37 |
| Paige-Detroit | 1911 |
|
Palmer Singer |
1909 |
|
Peerless |
1905, 09, 18 |
| Pennsylvania | 1909 |
|
Peugeot |
1913-17, 19-22, 49 |
| Phoenix | 2001 |
| Pirate | 1913 |
|
Plymouth |
1933, 46, 58, 67-71 |
| Pontiac | 1957, 59-60, 62, 75, 84, 87 |
|
Pope-Hartford |
1909-15 |
| Pope-Toledo | 1905 |
|
Porsche |
1966, 70, 87-90 |
| Porter | 1915 |
| Pratt & Whitney | 1967-68, 70-71 |
|
Premier |
1909, 14, 16, 19 |
| Rae | 1914 |
| Rainier | 1909 |
| Ralph Miller | 1948-53, 56 |
| Ram | 1980 |
| Rambler | 1909 |
| Rambler | 1967-71, 77 |
| Rassey | 1981 |
| Rayfield | 1912 |
| Regal | 1909, 11-12, 14 |
| Renault | 1905, 09-10, 15 |
| Reo | 1905, 11-12, 31 |
|
Repco |
1968-69 |
| Riley | 1946 |
| Rochet-Schneider | 1909 |
| Roland-Pilain | 1923 |
| Royal | 1910 |
| Sampson | 1939-41, 46 |
| Schacht | 1911-13, 15 |
| Selden | 1909 |
| Shannon | 1919 |
| Sharp Arrow | 1909 |
| Sievers | 1926, 28 |
| Simca | 1951 |
|
Simplex |
1909-13, 15 |
|
Sparks |
1936-41, 46-51 |
| Speedwell | 1910-11, 13 |
| S. P. O. | 1910 |
| Stafford | 1914-15 |
| Stanley | 1905 |
| Staver-Chicago | 1911 |
| Stearns | 1909, 16 |
| Sterling | 1915 |
| Stevens-Duryea | 1909 |
| Stoddard-Dayton | 1909-10, 12 |
| Studebaker | 1909, 13-14, 30-39, 41, 46-47, 52, 56 |
|
Stutz |
1914-20, 30-32 |
| Sunbeam | 1913-16, 19, 21 |
| Sunset | 1909, 11 |
| Talbot | 1929 |
| Talbot-Lago | 1941, 46-47 |
| Thomas | 1905, 09 |
| Thompson | 1965 |
| Touraine | 1913 |
|
Toyota |
1996-2005 |
| Tulsa | 1913, 15 |
|
Unknown |
1905, 09-40, 46-76, 78-89, 91, 93, 98, 2012 |
| Velie | 1910-11, 13, 15 |
| Voelker | 1937-41, 46, 48, 51-53, 78 |
| Warren-Detroit | 1910, 12 |
| Wayne | 1950-58 |
| Wehr | 1934, 37, 39-40 |
| Welch | 1909 |
| Westcott | 1910-12 |
|
White |
1905, 09, 12, 14-15, 19 |
|
Winfield |
1938-41, 46-48 |
| Winton | 1905 |
|
Wisconsin |
1911-17, 19 |